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However, irritation, injury, or infection of any of the tissues in the oral cavity can also lead to mouth sores. Sores in the mouth can occur with certain systemic diseases such as Crohns disease, Behcets syndrome, and systemic lupus erythematosus.

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There are several techniques wherein the conscious mind can gain some degree of control over the body healing system. Biofeedback is one method that enables the conscious mind to access the brain to input new instructions.

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